Two commercial laying hen flocks in Ohio have been struck by highly pathogenic avian influenza (HPAI), including one that involved more than 3 million birds.
The United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS) reported that the presence of HPAI was confirmed on February 21 in a commercial flock of 3,090,400 laying hens in Darke County, and another commercial flock of 84,800 commercial layers in Mercer County.
Ohio in 2025 alone has lost 66 commercial poultry flocks to HPAI – more than any other state. Nearly all of those flocks have been in Mercer and Darke Counties, which have respectively lost 43 and 20 commercial flocks.
Avian flu in Indiana
APHIS reported two more flock infections in Indiana, both confirmed on February 21.
Those two were a flock of 19,400 commercial meat turkeys in Washington County and a flock of 4,200 commercial duck breeders in Elkhart County.
Both flocks were previously reported as presumed positive cases by the Indiana State Board of Animal Health (BOAH).
Indiana has now lost 11 commercial poultry flocks to HPAI in 2025.
Avian flu in Missouri
APHIS also provided information on a case of HPAI in a flock of 13,000 commercial turkey breeder hens in Lawrence County, Missouri. That case was confirmed on February 12.
Missouri has now lost 21 commercial poultry flocks to HPAI in 2025.
View our continuing coverage of the global avian influenza situation.
To learn more about HPAI cases in commercial poultry flocks in the United States, Mexico and Canada, see an interactive map on WATTPoultry.com.
