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Pfizer Animal Health offers Poulvac E. coli, a spray vaccine against avian pathogenic approved for use by the poultry industry in the EU. The vaccine is based on a European isolate, and has been shown to provide a broad protection against field infections found in the region. It can be administered from one day of age, and studies have shown that it generates a strong immune response that reduces mortality for up to 12 weeks. The vaccine has a zero-day withdrawal period. Revaccination depending on local field pressure and risk assessment can be considered in consultation with a veterinarian.